Granit Xhaka strike caps commanding victory as Arsenal move four points clear at the top of the Premier League and inflicted a first defeat of the season on 10-man Tottenham.
Gunners beat Spurs with a 3-1 win in a pulsating north London derby.
Arsenal came into the game seeking to exact revenge for their costly 3-0 loss at the Tottenham Hotspur Stadium in May and started strongly, with Martinelli seeing an early effort saved by Lloris at his near post.
Spurs were largely pinned back in their own half but provided a warning of their own goal threat when Richarlison’s low shot from a free-kick had to be palmed away by an alert Aaron Ramsdale.
Arsenal’s opener arrived shortly afterwards, however, and it came from an unlikely source in Partey, whose wayward long-range shooting has long been a source of frustration to supporters.
Thomas Partey’s stunning, long-range opener (20) was cancelled out by Harry Kane’s penalty (31) after Gabriel Magalhaes had fouled Richarlison, but the hosts, dominant for much of the first period, took complete control of the game after the break.
Gabriel Jesus capitalised on a mix-up between Hugo Lloris and Cristian Romero to put Arsenal in front from close range (49) and Granit Xhaka struck a clinical third (67) after Emerson Royal had been red carded for a reckless foul on Gabriel Martinelli.
Spurs rarely threatened after that, failing to register a single shot on target in the second half, and their task was made tougher by Emerson’s deserved sending off for his wild lunge at Martinelli.
Xhaka, once again excellent in his new, more attacking midfield role, then made the result safe when he wrong-footed Eric Dier from Martinelli’s flick and powered a low effort beyond Lloris.
Arsenal had chances to turn a comfortable victory into a rout in the closing stages, with Lloris saving superbly from substitute Kieran Tierney, but in the end the three goals proved more than sufficient on an afternoon which sent optimism levels through the roof at the Emirates Stadium.
Arsenal coach Mikel Arteta, in an interview with BT Sport said: “From the beginning, we went for it. With amazing support, we created a great energy in the stadium and we deserved to win the game.
“We were free, we were courageous, brave and we went for it. This is what we demand the players to do.
“Again, Gabriel Jesus’ winning mentality, the way he trains every day, the confidence he brings to the team, he has taken us to a different level.
“You could feel the connection with the players, the staff and the crowd. I am so happy because it was a beautiful game, a beautiful day, and we’ve made our supporters very happy.”